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Protein A
Staphylococ c al Protein A Rec o mbinant
Catalog No. PRO-356
Synonyms:
Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococ c al protein A, SPA.
Introduction:
Protein A is a cell wall protein deriving from Staphylococ c us aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Rec o mbinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The rec o mbinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the rec o mbinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococ c us endotoxins and hemolysin).
Description:
Rec o mbinant Staphylococ c al Protein A produced in E.Coli is a non-glycosylated, Polypeptide chain having a molecular mass of 45 kDa.
Rec o mbinant Staphylococ c al Protein A is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear colorless solution.
Formulation:
The protein solution contains no additives.
Stability:
SPA should be stored at -20°C.